Quality

Novogen is a pharmaceutical company that adheres to the guidelines of Good Manufacturing Practice. Promensil Menopause is a standardised isoflavone supplement which contains the stated total isoflavone dose in the aglycone form in every tablet ^21,22. The quality of the products is of the highest standard, with the production facility regularly audited by the Therapeutic Goods Administration.

Despite government regulations which control the components of alternative therapies, adherence to the stated amounts of the components is not routinely assessed ²². A comparison of phytoestrogen supplements available in the United States, including Promensil, found that half of the products tested had isoflavone levels that deviated by more than 10% from the claimed value. There was a large variability in the composition of supplements, as determined by HPLC profiles, many containing peaks of unknown origin and chemical structure ²². This study confirmed the quality and standardisation of the Promensil product.

A similar study compared some of the products available in Australia, including Promensil. While only two products had total isoflavone contents close to the stated amount, only Promensil was found to have constant isoflavone content for all batches tested.